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Lawyers for Harvard University will argue in federal court on Monday that the federal government's freeze of more than $2 billion in grants and contracts is illegal and should be reversed.

In filings in U.S. District Court in Boston, Harvard's attorneys say the 

imposed by the Trump administration threaten vital research in medicine, science and technology. The school's lawsuit aims to block the Trump administration from withholding federal funding "as leverage to gain control of academic decisionmaking at Harvard."

The Trump administration has said it froze the funding because Harvard violated Title VI of the Civil Rights Act by failing to address antisemitism on campus.

The hearing is expected to last just one day. Harvard is asking the judge, Allison D. Burroughs, for a summary judgment in hope of speeding the matter along, though it's unclear when she might rule on that request. And, whichever way she decides, legal experts NPR talked with don't expect a full resolution anytime soon, given the likelihood that either side will appeal a ruling.

While Harvard is the only school in court, colleges and universities around the country are watching the proceedings closely. Dozens of other institutions have also had millions in federal grants frozen.

"Across the higher ed landscape, across the entire sector, institutions recognize that what happens in this case will really have a profound impact," says Jodie Ferise, a lawyer in Indiana who specializes in higher education and represents colleges and universities.

"There is nothing different about Harvard University than there is about some Midwestern, smaller private college," Ferise says. "Everyone is watching and worrying about the extent to which the federal government is seeking to control the higher education sector."

In court documents, Harvard's lawyers make several arguments. The first is that the administration violated the 

, known as APA, which says that federal agencies cannot abruptly change procedures without reason. They argue that there are procedures, established by Congress for "revoking federal funding based on discrimination concerns," that the government did not follow.

They argue the government didn't follow proper procedure when dealing with an alleged violation of federal civil rights law. This argument is a common complaint of groups suing the Trump administration, with more than 

 of the APA, according to the nonprofit Just Security, which tracks legal challenges to Trump administration actions.

Harvard also argues that there is no connection between alleged antisemitism and shutting down federal medical and scientific research.

"The Government has not—and cannot—identify any rational connection between antisemitism concerns and the medical, scientific, technological, and other research it has frozen that aims to save American lives, foster American success, preserve American security, and maintain America's position as a global leader in innovation," Harvard's complaint says.

The complaint also charges that the government is violating the First Amendment, which, it says, "does not permit the Government to 'interfere with private actors' speech to advance its own vision of ideological balance.' "

Harvard claims the government is interfering with its academic freedom by telling the university how to hire, how to admit students and by demanding access to student files without subpoenas.

The Trump administration accuses Harvard of failing to protect Jewish students. After Harvard refused to comply with a list of demands, the 

, a multiagency group within the administration that includes representatives of the Justice, Education, and Health and Human Services departments, announced it was freezing funds.

"The gravy train of federal assistance to institutions like Harvard, which enrich their grossly overpaid bureaucrats with tax dollars from struggling American families, is coming to an end," Harrison Fields, a White House spokesperson, said in a statement when the cuts were announced. "Taxpayer funds are a privilege, and Harvard fails to meet the basic conditions required to access that privilege."

The government argues that Harvard didn't follow federal law – including allegedly fostering antisemitism on campus and engaging in illegal discrimination through DEI efforts. As a result, the government argues, the university is not entitled to these research dollars.

"The Trump administration is looking at Harvard and saying, 'you failed to do things,' " explains Jessica Levinson, 

 in Los Angeles. " 'You failed to protect Jewish students. You failed to comply with a federal law. And as a result of those failures, we get to do something in return. We get to cut off the federal spigot of funding.' "

And while Levinson and other legal experts NPR talked with say that federal power is there, the question for the court will be: Did the Trump administration go about using that power in the right way?

The more than $2 billion at stake in this case supports more than 900 research projects at Harvard and its affiliates. Those grants fund studies that include Alzheimer's prevention, cancer treatment, military research critical for national security and the impact of school closures on mental health.

Kari Nadeau is a professor, physician and researcher at the Harvard T.H. Chan School of Public Health, who studies ways of reducing the risk of near-fatal allergies in infants. When the government cancelled her grant, she says she lost about $12 million for the study.

"We've had to stop our studies and our work," Nadeau says, "and that has really had a huge ripple effect for everyone. Not just us, but the people we serve, the teams we work with, the trainees that we train, as well as many staff across the country."

She's especially concerned with families who signed up to participate in the clinical trial, which was supposed to last for seven years. "When you take a therapy away from people, and especially in this case, children, and you put them at risk for a near fatal disease like food allergy, that is a safety issue," she says. "These families could be put into additional harm."

The future of her project may come down to the outcome of this case. She says she's cautiously optimistic.

Legal experts suggested the case will almost certainly not end with this hearing.

"Will Harvard win in Boston? There's a good chance of that," says Ferise. "But is that gonna settle the matter? That's probably not the case. It will go to an appeal, it will go to the Supreme Court. So a win, while it would be welcome to colleges, won't feel like the end of the story."

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With more than $2 billion dollars in federal research grants at stake, the two sides will argue before a federal judge as the university pushes back on the administration’s demands.

Lawyers for Harvard and Trump square off in court in Boston

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