Mayo Clinic announces next CEO: AI lead Dr. Matthew Callstrom

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Mayo Clinic officially has its next leader. The Mayo Clinic Board of Trustees announced Friday that it has elected Dr. Matthew Callstrom as its next president and CEO.
Callstrom, who has helped direct the hospital’s artificial intelligence program, will start Jan. 1, succeeding Dr. Gianrico Farrugia. Farrugia has served as Mayo Clinic’s CEO for eight years and announced his planned retirement earlier this year.
A Minnesota native, Callstrom has been with Mayo Clinic for nearly 25 years. He’s a physician-scientist and body interventional radiologist who has helped advance image-guided cancer treatment and develop technologies to more precisely identify and treat cancer.
Callstrom currently serves as medical director for Mayo Clinic’s Strategy Department and the Generative Artificial Intelligence program, helping integrate the use of AI into medicine, including efforts to detect diseases earlier.
“I am deeply honored to have the opportunity to lead Mayo Clinic in this moment, serving alongside colleagues whose expertise, curiosity and commitment to our patients inspire me every day,” Callstrom wrote in Friday’s news release. “Mayo Clinic has always been at its best when we bring the full power of our clinical expertise, science and innovation to the needs of the patient. Now, we have an opportunity to build on that foundation – accelerating the translation of discovery and emerging technologies into better care and extending Mayo Clinic’s impact to more patients, wherever they are."
Farrugia will continue serving as president through the end of the year. He said he will work closely with Callstrom to ensure a clean transition.
“It has been the privilege of my career to serve as president and CEO of Mayo Clinic and to work alongside extraordinary colleagues who share an unwavering commitment to patients,” Dr. Farrugia said. “Dr. Callstrom knows Mayo Clinic deeply, understands where healthcare is headed and has the vision and experience to build on the progress we have made. I have great confidence in him and in Mayo Clinic’s future.”
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